Specialized has several saddles designed for women and offers a 30 day trial to help find the right one. Does she have a quality pair of cycling shorts? Shorts can make the world of difference and many brands offer women specific designs.
On a different note, if you drive to the ride, consider parking on Mission Oaks off of SWPKY to ride TC. The good stuff is right down the road and will help to minimize any ill feelings from the neighborhood.