If it's just me, my favorite is to just throw the bike in the bed. Latest truck I bought had a 80" bed so I don't need to pull of a wheel or anything. I have to open up the tonneau if I leave the wheels on since my bars is pretty wide. I can fit the kids bikes in the bed and close up the tonneau, and then toss a hitch rack on the back too, and do like having the option to load up with gear in the bed, and hang a few bikes off the back if I need to.